Medical Glossary

Aldosteronism

Aldosteronism is the overproduction of the hormone aldosterone from the cortex (the outer layer) of the adrenal gland or a tumor containing that type of tissue. Excess aldosterone (pronounced al'-do-ster-one) results in low potassium levels (hypokalemia), underacidity of the body (alkalosis), muscle weakness, excess thirst (polydipsia), excess urination (polyuria), and high blood pressure (hypertension). Also called hyperaldosteronism or Conn's syndrome.disorder marked by excessive secretion of the hormone aldosterone, which can cause weakness, cardiac irregularities, and abnormally high blood pressure. Also called hyperaldosteronism.a condition characterized by the hypersecretion of aldosterone, occurring as a primary disease of the adrenal cortex or, more often, as a secondary disorder in response to various extraadrenal pathologic processes. Primary aldosteronism, also called Conn's syndrome, may be caused by adrenal hyperplasia or by an aldosterone-secreting adenoma. Secondary aldosteronism is associated with increased plasma renin activity and may be induced by nephrotic syndrome, cirrhosis, idiopathic edema, congestive heart failure, trauma, burns, or other kinds of stress. Also called hyperaldosteronism.